Main Page: Difference between revisions
m Setting up the main entry point to Wikimaladie. |
mNo edit summary |
||
| (4 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
<strong>Let's work together to unravel the mystery of Alzheimer's Disease.</strong> | <strong>Let's work together to unravel the mystery of Alzheimer's Disease.</strong> | ||
To find a cure for the disease, to find a disease changing medication, we must first understand the causal mechanisms at the origins of the disease, the aetiology. We currently have many hypotheses about potentially relevant mechanisms, but it should emphasized that we have no hypothesis about the primary origin. | "A full comprehension of the causes of a deadly disease is the essential prerequisite to find a cure." | ||
<ref> | |||
Behl, Christian. Alzheimer’s Disease Research: What Has Guided Research So Far and Why It Is High Time for a Paradigm Shift (p. 6). Springer International Publishing. Kindle Edition. | |||
</ref> | |||
To find a cure for the disease, to find a disease changing medication, we must first understand the causal mechanisms at the origins of the disease, the aetiology. We currently have many hypotheses about potentially relevant mechanisms in a causal chain, but it should be emphasized that we have no hypothesis about the primary origin. This should be contrasted with the situation for many other diseases. For sickle cell anemia we know the point mutation of this genetic disease. For the infectious disease AIDS, the primary cause is HIV, the human immunodeficiency virus. For various cancers, the origin is a set of mutations in a set of genes. In the Alzheimer's disease literature, this distinction between <i>primary cause</i> and relevant <i>causal mechanism in a causal chain</i> is lacking. Let's call hypotheses about the later [[non-primary mechanism hypotheses]] to be clear on this point. | |||
| Line 12: | Line 16: | ||
* [https://www.mediawiki.org/wiki/Special:MyLanguage/Localisation#Translation_resources Localise MediaWiki for your language] | * [https://www.mediawiki.org/wiki/Special:MyLanguage/Localisation#Translation_resources Localise MediaWiki for your language] | ||
* [https://www.mediawiki.org/wiki/Special:MyLanguage/Manual:Combating_spam Learn how to combat spam on your wiki] | * [https://www.mediawiki.org/wiki/Special:MyLanguage/Manual:Combating_spam Learn how to combat spam on your wiki] | ||
==Notes== | |||
<references /> | |||
Latest revision as of 05:51, 6 December 2025
Let's work together to unravel the mystery of Alzheimer's Disease.
"A full comprehension of the causes of a deadly disease is the essential prerequisite to find a cure." [1] To find a cure for the disease, to find a disease changing medication, we must first understand the causal mechanisms at the origins of the disease, the aetiology. We currently have many hypotheses about potentially relevant mechanisms in a causal chain, but it should be emphasized that we have no hypothesis about the primary origin. This should be contrasted with the situation for many other diseases. For sickle cell anemia we know the point mutation of this genetic disease. For the infectious disease AIDS, the primary cause is HIV, the human immunodeficiency virus. For various cancers, the origin is a set of mutations in a set of genes. In the Alzheimer's disease literature, this distinction between primary cause and relevant causal mechanism in a causal chain is lacking. Let's call hypotheses about the later non-primary mechanism hypotheses to be clear on this point.
Getting started
[edit | edit source]WikiMaladie uses MediaWiki, the same software that runs WikiPedia. Consult the User's Guide for information on using the wiki software.
- Configuration settings list
- MediaWiki FAQ
- MediaWiki release mailing list
- Localise MediaWiki for your language
- Learn how to combat spam on your wiki
Notes
[edit | edit source]- ↑ Behl, Christian. Alzheimer’s Disease Research: What Has Guided Research So Far and Why It Is High Time for a Paradigm Shift (p. 6). Springer International Publishing. Kindle Edition.